Analysis of the efficacy and safety of low-dose urokinase combined with ozagrel in treatment of progressive cerebral infarction
Zheng Shuwang
Published 2016-10-25
Cite as Chin J Pract Med, 2016,43(20): 28-29. DOI: 10.3760/cma.j.issn.1674-4756.2016.20.009
Abstract
ObjectiveTo investigate the clinical efficacy and safety of low dose of urokinase combined with sodium ozagrel in treatment of progressive cerebral infarction patients.
MethodsFrom 2012 December to December 2014, 100 patients with progressive cerebral infarction were randomly divided into study group and control group with 50 cases in each group. The control group was treated with low molecular dextran and ginkgo leaf injection for treatment, and patients in the study group were treated with low dose urokinase and sodium ozagrel treatment. The neurological condition and adverse reactions of the two groups were detected, analyzed and compared.
ResultsThe total efficiency of the patients in study group (94.0%) was significantly higher than that in the control group (74.0%), and the differences were significant(P<0.05).
ConclusionsLow dose of urokinase combined with sodium ozagrel has good effect on progressive cerebral infarction patients, and with mild adverse reactions, so it is worthy of popularization and application.
Key words:
Urokinase; Sodium ozagrel; Progressive cerebral infarction
Contributor Information
Zheng Shuwang
Department of Neurology, the People’s Hospital of Anqiu, Anqiu 262100, China