Original Article
Clinical efficacy of hypertonic saline nasal sinus irrigation after endoscopic surgery for chronic rhinosinusitis
Zhang Xuexing, Zhang Kui, Sun Shujun
Published 2020-02-25
Cite as Chin J Pract Med, 2020, 47(4): 88-91. DOI: 10.3760/cma.j.issn.1674-4756.2020.04.027
Abstract
ObjectiveTo explore the clincal efficacy of hypertonic saline nasal sinus irrigation after endoscopic surgery for chronic rhinosinusitis.
MethodsA total of 104 patients diagnosed as chronic rhinosinusitis in the Second People’s Hospital of Xinxiang from May 2014 to March 2017 were selected and divided into routine group and observation group according to the stratified random method. And all patients were given functional endoscopic sinus surgery and then given the corresponding antibiotics and glucocorticoids after operation. The routine group was given normal saline for irrigation, and observation group was given hypertonic saline for nasal sinus lavage. And their dosages was reduced according to the patients’ postoperative recovery, and patients were followed up at 6 months after operation. The improvements of postoperative luminal mucosa and clinical symptoms were observed in the two groups, and the mucosal epithelialization time of the surgical cavity was recorded, and the occurrence of adverse reactions during the follow-up was counted in the two groups.
ResultsThe total effective rate in routine group was significantly lower than that in observation group (76.9% vs. 92.3%, P<0.05). The mucociliary clearance rate in observation group was (6.15±2.15) mm/min, significantly higher than the (4.97±1.34) mm/min in routine group (P<0.05), and there was no significant difference in mucociliary clearance rate between the two groups 3 months after operation (P>0.05). The constituent ratios of the mucosal epithelialization time<4 weeks, 4 to 8 weeks, 8 to 12 weeks and>12 weeks were 1.9%, 25.0%, 46.2% and 26.9%, respectively, in routine group, and they were 3.8%, 51.9%, 26.9% and 17.3% respectively in observation group, which were significantly shorter than those in routine group (P<0.05). And there were no adverse reactions in the two groups.
ConclusionsHypertonic saline nasal sinus irrigation can significantly improve the surgical efficacy of endoscopic surgery, and promote the recovery of nasal mucosa function, with high safety.
Key words:
Nasal sinus lavage; Chronic rhinosinusitis
Contributor Information
Zhang Xuexing
Department of Otorhinolaryngology, Head and Neck Surgery, the Second People’s Hospital of Xinxiang, Xinxiang 453000, China
Zhang Kui
Department of Otorhinolaryngology, the Second People’s Hospital of Xinxiang, Xinxiang 453000, China
Sun Shujun
Department of Otorhinolaryngology, the Second People’s Hospital of Xinxiang, Xinxiang 453000, China
