Original Article
Application of MRI, DWI and SWI in screening cerebral microbleeds in patients with lacunar infarction
Liu Wentao, Dai Bo, Meng Qingcheng, Li Hailiang, Dou Xinmin
Published 2021-05-10
Cite as Chin J Pract Med, 2021, 48(9): 13-16. DOI: 10.3760/cma.j.cn115689-20210111-00161
Abstract
ObjectiveTo investigate the application value of magnetic resonance imaging (MRI), diffusion weighted imaging (DWI) and susceptibility weighted imaging (SWI) in screening cerebral microbleeds (CMBs) in patients with lacunar infarction (LI).
MethodsA total of 95 patients with highly suspected LI complicated by CMBs treated in Henan Cancer Hospital from May 2018 to April 2020 were selected as the research objects. All patients received MRI, DWI, SWI, and digital subtraction cerebral angiography (DSA) examinations. Taking results of DSA examination as the "gold standard" , the application value of MRI, DWI, SWI in screening CMBs in LI patients was analyzed.
ResultsAmong 95 patients with highly suspected LI complicated by CMBs, 79 cases were diagnosed with CMBs by DSA examination, accounting for 83.16%. According to the results of DSA examination, the diagnostic coincidence rates of MRI, DWI, SWI examination for patients with LI complicated by CMBs were 83.16%, 87.37%, and 92.63%, respectively; and the difference was not statistical significant (P>0.05). The results of MRI, DWI, SWI all had ideal consistency with DSA examination (Kappa value=0.477, 0.590, 0.743). There was no significant difference in sensitivity, accuracy, and specificity among MRI, DWI and SWI (P>0.05). In the T1-weighted imaging (T1WI) sequence of the MRI examination of the CMBs in patients with LI, it could be seen that there was a low signal or isosignal circular shadow in the infarct focus; T2-weighted imaging (T2WI) inspection showed slightly low-signal ring or similar circular shadows; DWI inspection showed low-signal dotted shadows; SWI inspection showed low-signal strip, ring or dot shadows with clear edges.
ConclusionsMRI, DWI and SWI has certain value in screening CMBs in patients with LI, in practical application. The performance of the three can be considered to determine their combination, in order to improve the accuracy of early diagnosis of the disease.
Key words:
Stroke, lacunar; Cerebral microbleeds; Magnetic resonance imaging; Diffusion weighted imaging; Susceptibility weighted imaging
Contributor Information
Liu Wentao
Department of Radiology, Henan Cancer Hospital, Zhengzhou 450000, China
Dai Bo
Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou 450000, China
Meng Qingcheng
Department of Radiology, Henan Cancer Hospital, Zhengzhou 450000, China
Li Hailiang
Department of Radiology, Henan Cancer Hospital, Zhengzhou 450000, China
Dou Xinmin
Department of Radiology, Henan Cancer Hospital, Zhengzhou 450000, China
