Clinical Sciences
Contrast-enhanced ultrasound characteristics of choroidal hemangioma
Haicheng She, Dongjun Li, Wenli Yang, Wei Chen, Ziyang Wang, Wenbin Wei
Published 2015-01-10
Cite as Chin J Exp Ophthalmol, 2015, 33(1): 51-54. DOI: 10.3760/cma.j.issn.2095-0160.2015.01.011
Abstract
BackgroundChoroidal hemangioma is a common benign intraocular tumor.Typical choroidal hemangioma is comparably easy to diagnose, but untypical one might be misdiagnosed as malignant tumor.Contrast-enhanced ultrasound (CEUS) has been used to diagnose multiple neoplasm for the past few years.However, the application of CEUSin ophthalmology is less.
ObjectiveThis study was to investigate the CEUS characteristics of choroidal hemangioma.
MethodsFifty-eight eyes of 58 patients who were diagnosed as choroidal hemangioma were included in Beijing Tongren Hospital during July 2010 to December 2012.CEUS was performed on the patients to check the manifestations of choroidal hemangioma.A time-intensity analysis was employed to quantitatively analyzed and compared the maximum intensity (MI), rising time (RT), time to peak (TTP), and mean transit time (mTT) between the choroidal hemangioma and normal orbital tissue and the parameters were contrasted using Wilcoxon signed-rank test.
ResultsCEUS showed that choroidal hemangioma was gradually enhanced by the contrast after intravenous injection of sulphur hexafluoride microbubbles with a high-reference signal in choroidal hemangioma, and the fading procedure was slower in choroidal hemangioma than that of normal orbital tissue.MI, RT, TTP, and mTT were 294.20% (217.35%, 373.25%), 21.30 (17.35, 23.35) s, 25.00 (21.68, 27.48) s and 59.30 (51.08, 78.35) s in the choroidal hemangioma, which were significantly higher than 100.00% (100.00%, 100.00%), 17.75 (15.00, 20.30) s, 22.40 (18.35, 24.63) s and 47.25 (40.90, 57.23) s in the normal orbital tissue (Z=-6.608, -4.998, -4.650, -4.332, all at P<0.001).
ConclusionsChoroidal hemangioma has its own CEUS manifestation characteristics. CEUS is helpful to the differential diagnosis of choroidal hemangioma.
Key words:
Choroid; Choroidal neoplasm/diagnosis; Hemangioma/diagnosis; Contrast-enhanced ultrasound
Contributor Information
Haicheng She
Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
Dongjun Li
Wenli Yang
Wei Chen
Ziyang Wang
Wenbin Wei