Clinicopathology is a clinical application technology of histomorphological examination on tissue biopsy specimens, gross sampling and slice, and a pathological diagnosis is obtained by combining with clinical manifestations, surgical findings, gross changes and the cell morphology change under the optical microscope and further immunohistochemistry and molecular biological detection on tissue sections, thus to accurately diagnose the disease and provide a reliable basis for pathological disease etiology, pathogenesis research, eye disease outcome and prognosis judgement.Ocular pathology was not only the gold standard of the diagnosis, but also a therapeutic tool for eye diseases.Ophthalmology is a surgery related clinical disciplines.In clinical work, we found that ignoring the pathological examination of resected tissue specimens is the primary cause of misdiagnosis and mistreatment of eye disease, diagnostic delays can also increase the disease deterioration and mortality risk.Ocular clinical and pathological examination is one of the specific measures to avoid misdiagnosis and mistreatment, it is suggested that ophthalmology clinicians pay attention to the pathological examination in order to carry out precise treatment of eye diseases.

Eye disease; Ophthalmic pathology; Differential diagnosis; Misdiagnosis; Precision medicine