Glaucoma is a common blinding eye disease mainly characterized by optic nerve damage.Lowing intraocular pressure is still the main managing method of glaucoma up to now.However, although the intraocular pressure is reasonably controlled, optic nerve damage is difficult to recovery and sustainable development in some patients.Therefore, the pathogenesis and prevention and treatment of glaucoma have always been the hot spot of the research of glaucoma in recent years.Even though the big progresses have been made in the experimental research of optical nerve injury and repair, little good evidence has been seen in the clinical management of glaucoma neuroprotection.In recent years, genomics study, stem cells study, molecular biological study, electronic technology application in medical research, especially the rise of big data era laid a good basis for the neuroprotection of glaucoma.Ophthalmologists should focus on new insights into the potential and beyond impact factors in the precise individual therapy of glaucoma neuroprotection.

Glaucoma; Neuroprotection; Precise individual therapy; Big data era