Clinical Science
Ocular surface change of primary pterygium with OCULUS keratograph
Zhongting Li, Xuan Leng, Yanli Zhang, Tingxin Hu, Qi Zhao, Minbin Yu
Published 2018-12-10
Cite as Chin J Exp Ophthalmol, 2018, 36(12): 942-945. DOI: 10.3760/cma.j.issn.2095-0160.2018.12.009
Abstract
ObjectiveTo study the correlation between pterygium area and the clinical manifestation and signs of primary pterygium obtained from OCULUS Keratograph.
MethodsA prospective case observation study was performed.Thirty-nine (55 eyes) primary pterygium patients were selected from June to September 2016 in Zhongshan People's Hospital.The area of the pterygium invaded cornea and duration of pterygium were recorded.The ocular surface condition was detected by corneal fluorescein staining.The break up time of tear film (BUT) and the gland function score were measured with OCULUS Keratograph.This study was approved by the Ethics Committee of Zhongshan People's Hospital(2015[13]). All operations followed the Helsinki Declaration and all patients signed informed consent forms.
ResultsThe areas of pterygium invaded cornea was 2-20 mm2, the mean size was 5(3, 10)mm2; the duration of pterygium was 3-8 years, the mean duration was 5(4, 6)years; the BUT was 2.1-15.0 seconds, the mean BUT was (6.3±3.0) seconds.The mean gland function score was 2(1, 3). The area of pterygium was not significantly correlated with the duration of pteryguim (r=0.197, P=0.148), while it was negatively correlated with BUT (r=-0.711, P<0.001 ) and positively correlated with the tarsal gland score (r=0.554, P<0.001). What's more, 82% (45/55 eyes) of the patients' tear film rupture appeared firstly near pterygium's head.
ConclusionOCULUS Keratograph can directly evaluate the ocular surface condition of pterygium patients in a non-contact and non-invasive method.Assessing the ocular surface damage by observing the area of pterygium invaded cornea may provide a prospective treatment for pterygium patients.
Key words:
Pterygium; OCULUS Keratograph; Break up time of tear film
Contributor Information
Zhongting Li
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
Department of Ophthalmology, Zhongshan City People's Hospital, Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China
Xuan Leng
Department of Ophthalmology, Zhongshan City People's Hospital, Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China
Yanli Zhang
Department of Ophthalmology, Zhongshan City People's Hospital, Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China
Tingxin Hu
Department of Ophthalmology, Zhongshan City People's Hospital, Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China
Qi Zhao
Department of Ophthalmology, Zhongshan City People's Hospital, Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China
Minbin Yu
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
