Pathological changes of advancing age-related macular degeneration (AMD) is characterized by outer retinal atrophy and thinning, degeneration, proliferation or atrophy of the retinal pigment epithelium, and the presence of macular neovascularization including geographic atrophy and wet AMD, which can seriously impair visual function.Currently, imaging modalities for detecting, quantifying, and monitoring the fundus of advancing AMD include color fundus photography, fundus autofluorescence, near-infrared reflectance, optical coherence tomography, fundus fluorescein angiography, and indocyanine green angiography.Advanced imaging modalities such as optical coherence tomography angiography, multicolor fundus photography, widefield photography, and multispectral imaging have also been widely used for imaging advancing AMD.The optimal selection of these imaging modalities is critical for detecting, quantifying, and monitoring advancing AMD, and may affect the timeliness and cost of clinical diagnosis and treatment.The main challenges currently facing advancing AMD imaging include selecting the best imaging modality and developing image analysis algorithms.However, there is currently no consensus on the traditional and contemporary advanced imaging modalities for detecting, quantifying, and monitoring advancing AMD, both domestically and internationally.Therefore, the consensus expert group conducted a systematic discussion on the various imaging modalities for advancing AMD, evaluated their advantages and disadvantages based on a large sample analysis of numerous clinical cases, and systematically summarized the role of each imaging modality in future research on advancing AMD.In combination of economic efficacy cost analysis, the consensus expert group put forward suggestions on choosing optimal techniques for diagnosis and monitoring of advancing AMD at different stages.

Macular degeneration, advancing; Geographic atrophy; Diagnosis; Retinal imaging; Consensus