To observe the effect of Roy adaptation model nursing intervention on self-perceived burden (SPB) and neutrophil granulocyte implantation of recipients after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

One hundred allo-HSCT recipients who got allo-HSCT in the Xinqiao Hospital of Army Medical University and in remission during July 2017 and May 2018 were enrolled and randomly divided into observation group and control group. After entering the laminar flow chamber, recipients in the control group adopted the routine health education and psychological nursing methods. Recipients in observation group were given Roy adaptation model intervention nursing based on the control group. Recipients filled the SPB scale when in and out of the laminar flow chamber. The group t test was used to compare the age, SPB score and neutrophil implantation time of recipients between the 2 groups, and the paired t test was used to compare the SPB score of recipients when in and out of the laminar flow chamber in each group. The χ² test was used to compare the gender, donor recipient matching type, donor recipient blood relationship, medical insurance type and incidence of SPB. P<0.05 was statistically significant.

While entering the laminar flow chamber, the SPB scale scores of recipients in observation group and control group were (31±5) and (32±4) respectively, which had no significant difference (t=0.15, P>0.05). When left the laminar flow chamber, the SPB scale scores of recipients in observation group were (25±6), which were lower than that of the control group (30±4)(t=4.66, P<0.05). The SPB scale scores of recipients at the time of leaving the laminar flow chamber was lower than that at the time of entering in the observation group (t=5.49, P<0.05). No significant difference was found for the SPB scale scores of recipients between leaving and entering the laminar flow chamber in the control group (t=1.71, P>0.05). At the time of entering the laminar flow chamber, the incidence of SPB was 92% (46/50) in the observation group and 96% (48/50) in the control group respectively, which had no significant difference (χ²=0.71, P>0.05). When left the laminar flow chamber, the incidence of SPB was 94% (47/50) in the control group and 74% (37/50) in the observation group, which had significant difference (χ²=7.44, P<0.05). The incidence of SPB at the time of leaving the laminar flow chamber was lower than that at the time of entering in the observation group (χ²=5.74, P<0.05). No significant difference was found for the incidence of SPB between leaving and entering the laminar flow chamber in control group (χ²=0.21, P>0.05). The mean time of neutrophil implantation in the experimental group (12.2±2.6) days was significantly less than that in the control group (17.1±2.7) days (t=9.41, P<0.05).

The application of Roy adaptation model nursing intervention can alleviate the severity of SPB, improve the adaptability and shorten the time of neutrophil implantation.

Roy adaptation model; Hematopoietic stem cell transplantation; Self-perceived burden; Neutrophil granulocyte implantation