To explored the clinical features of patients with recurrent isolated sleep paralysis (RISP), providing clues for the pathogenesis and treatment of the disease.

The clinical features and auxiliary examina-tions of 2 patients with recurrent isolated sleep paralysis diagnosed at the People��s Hospital of Zhengzhou University in 2017 were retrospectively analyzed.

Both cases were excluded from narcolepsy,which was consistent with the clas-sic performance of sleep paralysis. At the time of attack,the consciousness of Example 1 was not completely clear,the neck could be slightly twisted and accompanied by auditory hallucinations;Example 2 consciousness was completely clear and there was no hallucination. Both cases were accompanied by obvious symptoms of anxiety,but the causal relationship was not clear. Example 1 received trazodone treatment with good results.

RISP attacks are in a state of separa-tion,but in a variety of forms;Its recurrent attacks may be associated with impaired sleep homeostasis;A variety of antide-pressant drugs are effective for RISP.

Sleep paralysis; Rapid eye movement sleep period; Sleep homeostasis; Antidepressant drug