To analyze the effects of continuous pulmonary rehabilitation training combined with salmeterol and tiotropium bromide on the lung function and quality of life of patients with moderate to severe chronic obstructive pulmonary disease (COPD).

A total of sixty patients with moderate to severe COPD treated in People′s Hospital of Yicheng District of Zaozhuang from August 2017 to December 2018 were selected as the research objects.Divided into 2 groups according to the random number table method.The observation group received 30 patients, who received continuous pulmonary rehabilitation training combined with salmeterol and tiotropium bromide treatment.The control group received 30 patients who received conventional pulmonary rehabilitation training combined with salmeter.Roticasone powder inhalation and tiotropium bromide treatment.Observe and record the pulmonary function indexes of the two groups of patients when they were enrolled, on the first day of treatment, 2 weeks, 4 weeks and 8 weeks after treatment [ratio of forced expiratory volume to forced vital capacity in the first second (FEV₁/FVC), the percentage of forced expiratory volume in the first second (FEV₁%pred), and maximum voluntary ventilation (MVV) ], quality of life COPD assessment test (CAT) score, self-rating anxiety scale (SAS) score and self-rating depression scale (SDS) score, and then proceed statistical analysis.

The FEV₁/FVC, FEV₁%pred and MVV of the observation group were significantly increased at 2 weeks, 4 weeks and 8 weeks after treatment compared to the time when the group was enrolled.The FEV₁/FVC, MVV at 2 weeks after treatment in the control group and FEV₁%pred at 2 weeks and 4 weeks after treatment.The pred was significantly higher than that at the time of entry, the difference was statistically significant (P<0.05), and the difference in FEV₁/FVC, FEV₁%pred and MVV was also statistically significant in the two groups at 4 and 8 weeks after treatment (P<0.05). The CAT scores of the observation group at 2, 4, and 8 weeks after treatment were significantly lower than those at the time of entry, and the CAT scores of the control group at 2 weeks after treatment were significantly lower than those at the time of entry, the difference was statistically significant (P<0.05), and the difference in CAT scores between the two groups at 4 and 8 weeks after treatment was also statistically significant (P<0.05). The SAS score and SDS score in the observation group were significantly lower than those in the enrolled group at 2 weeks, 4 weeks, and 8 weeks after treatment.At that time, the SAS score and SDS score of the control group 2 weeks after treatment were significantly lower than those at the time of enrollment, the difference was statistically significant (P<0.05), and the SAS score and SDS score of the two groups were similar at 4 and 8 weeks after treatment.The ratio difference was also statistically significant (P<0.05).

Continuous pulmonary rehabilitation training combined with salmeterol ticasone powder inhalation and tiotropium bromide can better improve the symptoms of airway obstruction and psychological state of COPD patients, enhance their lung function, and improve their quality of life.

Pulmonary disease, chronic obstructive; Continuous lung rehabilitation training; Salmeterol tikasson; Tiotropium bromide; Lung function