To explore the independent risk factors for short-term death in ICU patients with acute respiratory failure.

The present study is a case control study, a random sampling method were performed to collect the clinical data of 100 patients with acute respiratory failure admitted to Department of Intensive Care Medicine, the Second People′s Hospital of Nantong from September 2018 to September 2021.The patients were divided into good prognosis group (survival, 54 cases) and poor prognosis group (death, 46 cases) according to their 30-Day survival condition.Basic information of patients in two groups was compared.The prognosis was considered to be a dependent variable (Y, poorness=1), the age, availability of combined multiple organ dysfunction syndrome, acute physiology and chronic health score Ⅱ (APACHE Ⅱ), minimum systolic blood pressure, maximum respiratory rate, minimum fingertip oxygen saturation, maximum total bilirubin and minimum plasma albumin were used as independent variables (X), and the independent risk factors for poor outcome in patients with acute respiratory failure were identified.

compared with the good prognosis group, the higher proportion of patients with age ≥75 years and combined with multiple organ dysfunction syndrome were found in the poor prognosis group; and APACHE Ⅱscore, maximum respiratory frequency and maximum blood total bilirubin in the poor prognosis group were significantly; the minimum blood pressure, minimum fingertip blood oxygen saturation and minimum plasma albumin of patients were significantly lower (all P<0.05). Multivariate logistic analysis confirmed that age ≥75 years, multiple organ dysfunction syndrome, APACHE Ⅱ score ≥20 points, minimum systolic blood pressure <80 mmHg (1 mmHg=0.133 kPa), maximum respiratory rate ≥29 beats/min, minimum fingertip oxygen saturation <92%, maximum total blood bilirubin ≥9.00 mg/L and minimum plasma albumin <28.00 g/L were independent risk factors for poor prognosis in patients with acute respiratory failure (all P<0.05).

Multiple factors impacting the 30-Day death of ICU patients with acute respiratory failure including the age, multiple organ dysfunction syndrome, APACHE Ⅱ score, minimum systolic blood pressure, maximum respiratory rate, minimum fingertip oxygen saturation, maximum total bilirubin and minimum plasma albumin, which should be cared by clinicians.

Intensive care units; Death; Risk factors; Acute respiratory failure