Clinical Research
Effect of autonomous motivation on the severity and short-term clinical effcacy of depression
Li Nian, Liu Kezhi, Lei Wei, Chen Jing, Xiang Bo, Liang Xuemei
Published 2018-01-20
Cite as Chin J Behav Med & Brain Sci, 2018, 27(1): 47-51. DOI: 10.3760/cma.j.issn.1674-6554.2018.01.010
Abstract
ObjectiveTo investigate the traits of autonomous motivation and its effect on the depression severity and short-term clinic outcome.
MethodsBehavioral Approach System and Behavioral Inhibition System Scale (BAS / BIS), Motivational Traits Questionnaire Short Form (MTQ), the Hamilton Depression Scale (HAMD-17) and the Hamilton Anxiety Scale(HAMA) were applied to 82 depression patients(case group) at baseline and after 2 weeks of treatment and 82 gender-matched healthy controls(control group). The reduction rate of HAMD total scores before and after treatment was used as the main efficacy indicator.
ResultsThe scores of MTQ-desire to learn((30.37±6.78) vs (33.72±4.34))and MTQ-mastery ((28.68±6.24) vs (32.29±4.74)), BAS-drive scores((9.90±2.76) vs (11.18±2.13)) were significantly lower in the case group than those in the control group, and the difference was statistically significant (all P<0.001), While the scores of MTQ-emotionality((36.26±7.14)vs (27.29±5.73)), MTQ-worry((40.87±7.56) vs (33.69±6.38)), BIS scores((22.68±2.61) vs (15.51±3.62)) were significantly higher than those in the control group, the difference was statistically significant (all P<0.01). Correlation analysis found that baseline HAMD-17total scores were significantly positively correlated with baseline HAMA total scores(r=0.666, P<0.05), BIS(r=0.278, P<0.05), MTQ-worry(r=0.264, P<0.05)and MTQ- emotionality(r=0.371, P<0.05). Baseline HAMA total scores were significantly positively correlated with baseline HAMD-17 total scores(r=0.666, P<0.05), MTQ-worry(r=0.228, P<0.05)and MTQ-emotionality(r=0.282, P<0.05). The reduction rate of HAMD-17 and HAMA in patients with 2 weeks of treatment was respectively used with stepwise regression analysis, which showed that the significant contribution of MTQ- mastery and BAS-drive, and explained the reduction rate variables 19% (R2=0.19) of HAMD. BAS-drive contributed significantly, and explained the reduction rate variables 16.9% (R2=0.169) of HAMA.
ConclusionAutonomous motivation levels of depression patients are significantly lower than that of healthy controls, while higher levels of autonomous motivation (BAS-drive) may be associated with better short-term clinic outcome.
Key words:
Depression; Autonomous motivation; Motivational traits; Outcome
Contributor Information
Li Nian
Clinical Medical School, Southwest Medical University, Luzhou 646000, China
Psychiatry Department, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
Liu Kezhi
Clinical Medical School, Southwest Medical University, Luzhou 646000, China
Psychiatry Department, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
Lei Wei
Clinical Medical School, Southwest Medical University, Luzhou 646000, China
Psychiatry Department, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
Chen Jing
Clinical Medical School, Southwest Medical University, Luzhou 646000, China
Psychiatry Department, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
Xiang Bo
Clinical Medical School, Southwest Medical University, Luzhou 646000, China
Psychiatry Department, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
Liang Xuemei
Clinical Medical School, Southwest Medical University, Luzhou 646000, China
Psychiatry Department, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
