Waardenburg syndrome is a hereditary disease with deafness and pigmentation abnormalities as the main manifestation. Because of its many pathogenic genes, and the mechanism of the interaction between the various pathogenic genes is very complicated, leading to a high heterogeneity of clinical manifestations, which causes great difficulties to the clinical classification of the diagnosis and treatment of the disease. This article focuses on describing the epidemiology, classification, clinical manifestations of the syndrome, in order to provide a reference for clinical diagnosis and treatment of the disease and scientific research.

Waardenburg's Syndrome; Hearing Loss; Pigmentation Disorders