Clinical Report
Clinical outcomes and treatment of early stage of corneal heterotopic pregnancy
Yaqin Wang, Qinghong Zhao, Wangming Xu, Jing Yang
Published 2018-07-25
Cite as Chin J Reprod Contracep, 2018, 38(7): 583-587. DOI: 10.3760/cma.j.issn.2096-2916.2018.07.012
Abstract
ObjectiveTo explore the clinical outcomes and treatment of early stage of corneal heterotopic pregnancy for desired fertility women.
MethodsThe clinical data were analyzed in 16 cases with early stage of cornual pregnancy diagnosed by ultrasound who underwent stimulate ovulation, intrauterine insemination (IUI), in vitro fertilization (IVF)-embryo transfer (ET) in our hospital.
ResultsSixteen cases of asymptomatic patient with early stage of cornual pregnancy opted for expectant treatment by close ultrasound monitoring. Eight cases gestation sac expanded to the horn of uterus, 2 cases remained in original site, 5 cases shifted to cavity and 1 case occurred spontaneous abortion. Seven cases of expanded to horn of uterus were offered with surgery while 3 cases were successfully treated by transvaginal ultrasound guided selective embryo reduction, 1 case of spontaneous abortion was successfully treated by methotrexate and mifepristone with curettage.
ConclusionIt’s possible that cornual pregnancy turns into uterine pregnancy, therefore early ultrasonographic diagnosis and close ultrasonographic and clinical monitoring within 8 weeks of pregnancy maybe provide important principles of treatments of specific measures which include observation and interruption of pregnancy for desired fertility patients with early stage of cornual pregnancy.
Key words:
Cornual pregnancy; Fertility desire; Ultrasound; Diagnostics; Monitor; Treatment
Contributor Information
Yaqin Wang
Reproductive Medical Center, Renmin Hospital, Wuhan University, Wuhan 430060, China
Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan 430060, China
Qinghong Zhao
Department of Ultrasound, Wuhan University, Wuhan 430060, China
Wangming Xu
Reproductive Medical Center, Renmin Hospital, Wuhan University, Wuhan 430060, China
Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan 430060, China
Jing Yang
Reproductive Medical Center, Renmin Hospital, Wuhan University, Wuhan 430060, China
Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan 430060, China