Review
Diagnosis and treatment strategy of gastric cancer with ovarian metastasis
Yantao Tian, Fuhai Ma
Published 2019-03-23
Cite as Chin J Oncol, 2019, 41(3): 178-182. DOI: 10.3760/cma.j.issn.0253-3766.2019.03.004
Abstract
Ovary is one of the common metastatic sites of gastric cancer. In the female patients, ovarian relapse is one of the most important causes of treatment failure for gastric cancer. The most likely mechanism of Krukenberg tumor development is via retrograde lymphatic spreading from gastric cancer. However, neither optimal treatment strategy nor standard treatment guideline for Krukenberg tumor from gastric cancer has been clearly established.The diagnostic key points consist of the previous or concomitant history of gastric cancer and the detection of ovarian solid tumors.The therapeutic regimens mainly include the metastasectomy, chemotherapy, radiotherapy and comprehensive treatment. Surgical resection of metastatic tumor combined with adjuvant chemotherapy can improve the prognosis and survival.
Key words:
Gastric neoplasms; Neoplasms metastasis, ovary; Krukenberg tumor; Treatment
Contributor Information
Yantao Tian
Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Fuhai Ma