Benign central airway stenosis is associated with abnormal wound healing.Multiple cytokines and inflammatory cells take part in the different stages of wound healing. Cytokines, such as transforming growth factor-β, platelet-derived growth factor and vascular endothelial growth factor, play different roles in the formation of benign central airway stenosis.The studies on the mechanism of cytokine action are helpful to understand the pathogenesis of benign central airway stenosis and to propose possible therapeutic intervention targets.

Benign central airway stenosis; Wound healing; Transforming growth factor-β; Platelet-derived growth factor; Vascular endothelial growth factor