Analysis study of the recurrence and metastasis cases in early and local advanced cervical cancers after operation
Li Yudi, Ling Kaijian, Deng Li, Hu Qunying, Chen Yong, Tang Shuai, Song Bin, Zhang Wenxi, Yao Yuanyuan, Yu Meijia, Cheng Lijuan, Zhou Dan, Li Zhen, Gan Hua, Wang Wenting, Deng Yan, Wang Yanzhou, Liang Zhiqing
Abstract
ObjectiveTo explore the differences of the clinical features in recurrence patterns after surgery, in early and local advanced cervical cancers. We hope to provide evidence to guide follow-up and postoperative management.
MethodsCases with cervical cancer who underwent radical surgery and/or adjuvant therapy at the First Affiliated Hospital of the Third Military Medical University from January 2011 to December 2016, experienced recurrence and metastasis have been collected. The data were divided into early (107 patients) and locally advanced(58 patients) cervical cancer two groups based on FIGO stage. Retrospective a was performed to compare the two groups: the lymph node metastasis, histological type and other pathological characteristics, recurrence time and interval, recurrence and metastasis type and site (local pelvic, distant or multiple site).
ResultsA total of 1 784 cases included, which were followed up for an average of 60 months, and 65 patients were lost to follow-up after surgery (3.6%). There were 165 patients with recurrence and metastasis (9.2%). The lymph node metastasis of early group higher than the locally advanced group, P<0.05. There was no significant difference in the clinical features between the two groups: histological type, degree of tumor differentiation, deep stromal invasion or lymphovascular space invasion cancer (P>0.05). The median time of the recurrence and metastasis was 16 or 17 months, respectively. There was no statistical difference in the recurrence time and type between the two groups (P>0.05), the frequent site of recurrence was the pelvic cavity.
ConclusionThis study suggested that FIGO staging was not associated with recurrence time and space. There was no significant difference in recurrence patterns between early cervical cancer and locally advanced cervical cancer. The study showed that follow-up should be strengthened within 2 years after surgery.
Key words:
Laparoscopic surgery; Early cervical cancer; Locally advanced cervical cancer; Recurrence and metastasis
Contributor Information
Li Yudi
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Ling Kaijian
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Deng Li
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Hu Qunying
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Chen Yong
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Tang Shuai
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Song Bin
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Zhang Wenxi
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Yao Yuanyuan
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Yu Meijia
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Cheng Lijuan
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Zhou Dan
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Li Zhen
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Gan Hua
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Wang Wenting
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Deng Yan
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Wang Yanzhou
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
Liang Zhiqing
Department of Obstetrics and Gynecology, The First Affiliated Southwest Hospital of Army Military Medical University, Chongqing 400038, China
