Clinical Research
Association between somatization symptoms and BMI, sleep and cognitive function in patients with depression
Lu Yue, Li Jiasi, Zhou Shu, Wu Wen, Chen Chao, Gu Zhengsheng, Yin Ge, Sun Rui, Wang Ruoru, Bi Xiaoying
Published 2021-02-20
Cite as Chin J Behav Med & Brain Sci, 2021, 30(2): 134-138. DOI: 10.3760/cma.j.cn371468-20200702-01529
Abstract
ObjectiveTo study the relationship between somatization symptoms and body mass index (BMI), sleep and cognitive function in patients with depression.
MethodsA total of 119 patients with depression were selected from January to December in 2019.According to the score of patient health questionnaire-15(PHQ15), they were divided into mild somatization group (n=75) and moderate severe somatization group (n=44). Hamilton depression scale-24(HAMD-24), patient health questionnaire-15, Pittsburgh sleep quality index(PSQI) and Montreal cognitive assessment(MoCA) were used to evaluate all subjects.SPSS 23.0 software was used for data analysis.Independent sample t-test was used to compare BMI, sleep and cognitive function scores between the two groups.Pearson correlation analysis was used to study the correlation between somatization symptoms and sleep quality and cognitive function.
ResultsThere were significant differences in BMI((21.70±3.09)kg/m2, (23.31±3.51)kg/m2), PSQI((12.56±4.37), (14.37±3.72)), sleep quality(1.87±0.86), (2.21±0.80)), sleep disorder ((1.24±0.59), (1.65±0.53))and daytime dysfunction((2.45±0.81), (2.77±0.48)) between the two groups (t=-3.783--2.133, all P<0.05), but no difference was found in cognition (P>0.05). Correlation analysis showed that after controlling HAMD, PHQ-15 was positively correlated with PSQI, sleep quality, sleep disorder, daytime dysfunction and language score in MoCA (r=0.205-0.298, all P<0.05).
ConclusionThe severity of somatization in patients with depression is related to BMI, sleep quality, sleep disorder, daytime dysfunction and language function, suggesting that they may play an important role in the pathogenesis of depression with somatization.
Key words:
Depression; Somatization; Sleep quality; Cognition; BMI
Contributor Information
Lu Yue
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Li Jiasi
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Zhou Shu
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Wu Wen
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Chen Chao
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Gu Zhengsheng
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Yin Ge
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Sun Rui
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Wang Ruoru
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
Bi Xiaoying
Department of Neurology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
