Original Article
Prevalence and associated risk factors of pre-hypertension and hypertension in young and middle-aged population in Nanjing
Xiong Xiaolu, Ma Yiming, Zhou Weihong, Zhu Dalong, Xu Rong
Published 2021-04-01
Cite as Chin J Intern Med, 2021, 60(4): 338-344. DOI: 10.3760/cma.j.cn112138-20200817-00759
Abstract
ObjectiveTo investigate the prevalence and associated risk factors of pre-hypertension and hypertension in young and middle-aged population in Nanjing.
MethodsSubjects of the study were those who underwent physical examination in the physical examination center of Nanjing Drum Tower Hospital from 2009 to 2016. The prevalence and risk factors of pre-hypertension and hypertension in young (aged 18-44 years old) and middle-aged people (aged 45-59 years old) were analyzed.
ResultsA total of 142 857 participants aged 18-59 years old were analyzed. Among them, 64 220 cases in the pre-hypertension group and 13 912 cases in the hypertension group. The prevalence of hypertension was 9.74% (12.51% in males and 5.82% in females). The prevalence of pre-hypertension was 44.95% (53.31% in males and 33.15% in females). In the middle-aged group, the prevalence of pre-hypertension and hypertension were 51.68% and 15.13%, respectively, which was higher than that in the young group (37.95% and 4.13%, respectively). The prevalence of pre-hypertension and hypertension in 2013-2016 was 45.37% and 10.65%, respectively, which was higher than that in 2009-2012(44.52% and 8.78%). In addition, the prevalence of abnormal blood glucose metabolism, abnormal blood lipid metabolism and abnormal glucose and lipid metabolism in the pre-hypertension group was higher than that in the normal blood pressure group, but lower than that in the hypertension group (P<0.001). A logistic regression analysis indicated that age, overweight or obesity, hyperglycemia, hypertriglyceridemia and hypercholesterolemia were risk factors of pre-hypertension in male. Age, overweight or obesity, hyperglycemia, hypertriglyceridemia, hypercholesterolemia and hyper-low density cholesterolemia were associated with hypertension in male and with pre-hypertension and hypertension in female.
ConclusionsMiddle age, overweight/obesity, elevated fasting plasma glucose, elevated triglyceride and elevated total cholesterol were risk factors of pre-hypertension and hypertension in both men and women. Intervention on the related risk factors should be conducted as early as possible.
Key words:
Hypertension; Pre-hypertension; Risk factors; Cross-sectional study
Contributor Information
Xiong Xiaolu
Department of Rehabilitation,Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
Ma Yiming
Department of Medical Iconography, Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
Zhou Weihong
Department of Health Management Center, Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
Zhu Dalong
Department of Endocrinology
Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
Xu Rong
Department of Rehabilitation,Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
