To analyze the hemodynamic and ultrasonic characteristics of color Doppler ultrasonograph in benign and malignant bone tumors.

A total of 110 patients with bone tumors treated in Tumor Hospital Affiliated to Zhengzhou University from February 2017 to September 2020 were selected, and all of them underwent color Doppler ultrasonograph. Taking the pathological diagnosis results as the gold standard, the diagnostic value of color Doppler ultrasonograph for bone tumor was analyzed. The blood flow grading, hemodynamic parameters and ultrasonic characteristics of benign and malignant bone tumors were analyzed.

Pathological diagnosis confirmed 43 malignant cases and 67 benign cases. And color Doppler ultrasound confirmed 46 malignant cases and 64 benign cases. The sensitivity, specificity, accuracy, missed diagnosis rate, and misdiagnosis rate of color Doppler ultrasonograph were 93.02% (40/43), 97.01% (65/67), 95.45% (105/110), 6.98% (3/43) and 8.96% (6/67), respectively. The blood flow grading of malignant bone tumors was better than that of benign tumors (P<0.05). Compared with benign bone tumors, malignant bone tumors had lower resistant index and pulsatility index, but had higher peak systolic velocity, end diastolic velocity, maximum velocity, and minimize velocity (P<0.05). Malignant bone tumors were mainly characterized by infiltration of peripheral soft tissue (83.72%, 36/43) and discontinuous destruction of bone cortex (95.35%, 41/43), while benign bone tumors were characterized by no infiltration of peripheral soft tissue (82.09%, 55/67) and no continuous destruction of bone cortex (88.06%, 59/67), the differences between benign and malignant bone tumors was significant(P<0.05).

Color Doppler ultrasound has a good value in differential diagnosis of benign and malignant bone tumors, and there are significant differences in hemodynamic and ultrasonic characteristics between benign and malignant bone tumors . It can provide rich information support for clinical differential diagnosis.

Tumor; Bone; Color Doppler ultrasonograph; Hemodynamics