Symposium
Advances in research of interchangeable immunization with live attenuated Japanese encephalitis vaccines and inactivated vaccines
Deng Xuan, He Hanqing, Zhou Yang, Yan Rui, Tang Xuewen, Zhu Yao, Xu Xiaoping, Lyu Huakun
Published 2022-05-06
Cite as Chin J Prev Med, 2022, 56(5): 554-560. DOI: 10.3760/cma.j.cn112150-20211110-01044
Abstract
Japanese encephalitis (JE) virus is the leading cause of vaccine-preventable encephalitis in Asia and the Western Pacific, which mainly invades central nervous system. Vaccination is the most important strategy to prevent JE. Currently, both live attenuated Japanese encephalitis vaccines (JE-L) and inactivated vaccines (JE-I) are in use. Due to the supply of vaccines and the personal choice of recipients, there will be a demand for interchangeable immunization of these two vaccines. However, relevant research is limited. By reviewing domestic and foreign research evidence, this article summarizes the current situation of the interchangeable use of JE-L and JE-I, and makes recommendations when the interchangeable immunization is in urgent need, so as to provide reference for practical vaccination and policymaking in China
Key words:
Japanese encephalitis; Japanese encephalitis vaccines; Live attenuated JE vaccine; Inactivated JE vaccine; Interchangeable immunization
Contributor Information
Deng Xuan
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
He Hanqing
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Zhou Yang
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Yan Rui
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Tang Xuewen
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Zhu Yao
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Xu Xiaoping
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Lyu Huakun
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
