Original Article
Clinical features and treatment in patients with renovascular hypertension caused by renal arterial fibromuscular dysplasia
Ma Zhiling, Zhou Zhibin, Hua Zhaohui, Jiao Zhouyang, Xu Peng, Cao Hui, Liu Shirui, Li Zhen
Published 2022-06-25
Cite as Chin J Gen Surg, 2022, 37(6): 447-451. DOI: 10.3760/cma.j.cn113855-20211118-00670
Abstract
ObjectiveTo analyze the clinical characteristics and treatment of patients with renovascular hypertension (RVH) caused by renal arterial fibromuscular dysplasia (FMD).
MethodsClinical data and treatment result of 38 patients with renal arterial FMD and RVH admitted to our hospital from Jan 2014 to Dec 2020 were reviewed.
ResultsA total of 38 patients were enrolled in this study. Renal artery CTA showed that 40 renal arteries were involved, among these 6 branches had multifocal stenosis, and 34 branches had focal stenosis. Thity-three patients received surgical treatment, of which 32 patients underwent percutaneous transluminal renal angioplasty (PTRA), and 1 patient with renal aneurysm underwent renal artery stent implantation combined with aneurysm coil embolization. Postoperative blood pressure was significantly lower than that before the operation [(129.79±17.63) mmHg vs. (178.52±28.63) mmHg,t=-11.42,P<0.001]. The mean follow-up time was 35.5 months. Renal artery restenosis occurred in 4 patients and underwent reintervention.
ConclusionFor patients with renal arterial FMD and RVH, PTRA is safe and effective, especially for patients with focal lesions, with fair short and mid-term prognosis.
Key words:
Fibromuscular dysplasia; Renal artery; Hypertension; Percutaneous transluminal angioplasty; Drug-coated balloon
Contributor Information
Ma Zhiling
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Zhou Zhibin
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Hua Zhaohui
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Jiao Zhouyang
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Xu Peng
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Cao Hui
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Liu Shirui
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Li Zhen
Department of Endovascular Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
