Embryo implantation is a complex process that relies on elaborate cooperation between the well-qualified embryo and endometrial receptivity, and synchronous and harmonious communication between embryo and endometrium. Compared with the well-developed embryo culturing technology, there is a lack of effective diagnosis and treatment of endometrial receptivity. Traditional diagnostic tools, including pinopode analyzing, histologic dating, ultrasound, etc. are being questioned for accuracy and reproducibility. However, with the great development of omics, describing diseases in a gene expression whole pattern becomes feasible, which shows potential clinical value. The review focuses on the research progress of transcriptomic study in endometrial receptivity and concludes receptivity-related coding and non-coding RNAs, laying foundations for further research and clinical applications.

Endometrial receptivity; Window of implantation; Transcriptome profiling; Messenger RNA; Non-coding RNA