Review Article
Research progress on total skin irradiation using helical tomotherapy
Wang Haiyang, Pi Yifei, Liu Chunbo, Han Bin, Kong Fanyang, Ji Tengfei, Pei Xi, Xu Xie George, Guo Yuexin
Published 2022-12-15
Cite as Chin J Radiat Oncol, 2022, 31(12): 1185-1189. DOI: 10.3760/cma.j.cn113030-20210929-00246
Abstract
Cutaneous T-cell lymphomas are a relatively rare group of mature T-cell lymphomas mainly manifesting in the skin, and its common subtype is mycosis fungoides. Total skin electron irradiation is one of the important conventional treatment methods, but there are many disadvantages, such as uneven dose distribution, poor position repetition, and long treatment time, which affect the clinical efficacy and patient prognosis. With the emergence and gradual popularization of helical tomotherapy in recent years, more and more medical institutions are gradually expanding their applications in total skin irradiation due to their ability to treat ultra-long targets and achieve dose-sculpted distribution, aiming to further explore its good or bad, and confirm whether it can replace the traditional total skin electron irradiation. In this article, research progress on total skin irradiation using helical tomotherapy was reviewed, the development of treatment technology, clinical efficacy and current concerns and controversies were illustrated.
Key words:
Helical tomotherapy; Total skin irradiation; Lymphoma, T-cell, Cutaneous; Mycosis fungoides
Contributor Information
Wang Haiyang
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Institute of Nuclear Medical Physics, University of Science and Technology of China, Hefei 230026, China
Pi Yifei
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Liu Chunbo
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Han Bin
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Kong Fanyang
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Ji Tengfei
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
Pei Xi
Institute of Nuclear Medical Physics, University of Science and Technology of China, Hefei 230026, China
Xu Xie George
Institute of Nuclear Medical Physics, University of Science and Technology of China, Hefei 230026, China
Guo Yuexin
Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China
