Review
Research advances of stem cell-based tissue engineering repair materials in promoting the healing of chronic refractory wounds on the body surface
Peng Yu, Meng Hao, Li Pinxue, Jiang Yufeng, Fu Xiaobing
Published 2023-03-20
Cite as Chin J Burns, 2023, 39(3): 290-295. DOI: 10.3760/cma.j.cn501225-20220407-00126
Abstract
Repairing chronic refractory wounds on the body surface is a complex medical problem involving all stages of wound healing. In recent years, stem cells (SCs) and tissue engineering (TE) have brought hope for repairing chronic refractory wounds. SCs have excellent regenerative and paracrine effects; various TE strategies have the potential to repair chronic refractory wounds on the body surface and also improve the delivery efficiency of SCs. This article reviews the pathological characteristics of chronic refractory wounds, SCs used to repair chronic refractory wounds, and SC-based TE wound repair strategies.
Key words:
Stem cells; Tissue engineering; Regenerative medicine; Chronic wound; Wound repair
Contributor Information
Peng Yu
Research Center for Wound Repair and Tissue Regeneration, Medical Innovation Research Department, the PLA General Hospital, Beijing 100048, China
Meng Hao
Research Center for Wound Repair and Tissue Regeneration, Medical Innovation Research Department, the PLA General Hospital, Beijing 100048, China
Li Pinxue
School of Medicine, Nankai University, Tianjin 300071, China
Jiang Yufeng
Department for Wound Repair and Plastic Surgery, PLA Strategic Support Force Characteristic Medical Center, Beijing 100005, China
Fu Xiaobing
Research Center for Wound Repair and Tissue Regeneration, Medical Innovation Research Department, the PLA General Hospital, Beijing 100048, China
School of Medicine, Nankai University, Tianjin 300071, China
