To investigate the effect of drug intervention in extracorporeal shock wave lithotripsy (ESWL) on ureteral calculi.

A total of 163 patients with ureteral calculi admitted to our hospital from September 2019 to March 2021 were divided into control group (81 cases) and observation group (82 cases). The control group underwent conventional extracorporeal lithotripsy with B-ultrasound positioning. On the basis of the control group, the observation group took tamsulosin hydrochloride sustained-release tablets 0.2 mg and furosemide tablets 20 mg respectively 5 hours and 30 minutes before lithotripsy. The positioning time, lithotripsy time and shock wave impact times, lithotripsy effect (stone fragmentation distance, stone complete crushing rate and intraoperative stone removal rate) and the incidence of complications during lithotripsy were observed.

There was no drop-out in the two groups.There was significant difference between the observation group and the control group in stone positioning time (P<0.01). There was no difference in the time of lithotripsy and the frequency of shock wave between the two groups (P>0.05). Observation group of scattered stone rupture distance was higher than the control group, the difference was statistically significant (P<0. 01). Observation group of complete crushing rate, intraoperative stones clearance rate were higher than control group, difference between the two groups was statistical significance (P<0. 05).

Drug intervention extracorporeal shock wave lithotripsy in the treatment of ureteral calculi has created a good water environment for lithotripsy, short positioning time, high intraoperative stone removal rate and complete stone crushing rate, which is safe and feasible, and laid a foundation for smooth stone removal after operation.

Ureteral Calculi; Extracorporeal Shockwave Therapy; Drug Therapy; Lithotripsy