Review
Related factors of perinatal Escherichia coli infection
Ge Xiaoling, Wang Yajuan
Published 2023-06-16
Cite as Chin J Perinat Med, 2023, 26(6): 523-525. DOI: 10.3760/cma.j.cn113903-20221130-00998
Abstract
Escherichia coli is an important pathogen causing neonatal infectious diseases, such as neonatal meningitis and sepsis, and poses a great threat to the health of neonates. Currently, no effective screening and prevention measures are available. This article briefly reviews the rates of Escherichia coli colonization in pregnant women and newborns, the risk factors of colonization and transmission from mother to infant and the influences of Escherichia coli on pregnancy outcome, especially the harm to newborns. In clinical practice, more attention should be paid to high-risk pregnant women and the possible adverse pregnancy outcomes. For newborns born to mothers with Escherichia coli colonization, the possibility of Escherichia coli infection should be considered first if early meningitis and septicemia occur, which would be of great significance for the selection of antibiotics.
Key words:
Escherichia coli; Escherichia coli infection; Infectious disease transmission, vertical; Pregnancy outcome
Contributor Information
Ge Xiaoling
Department of Neonatology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China
Department of Neonatology, Maternal and Child Health Hospital of Changping District, Beijing 102200, China
Wang Yajuan
Department of Neonatology, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China