Review
Research progress of the influence of energy deficiency on female reproductive health
Lu Ye, Chen Chao, Zhou Yifan, Zhao Yuting, Wang Yulu, Chen Hang, Zhang Feifei, Li Xin
Published 2023-08-25
Cite as Chin J Reprod Contracep, 2023, 43(8): 847-851. DOI: 10.3760/cma.j.cn101441-20221027-00475
Abstract
Women need amounts of energy to develop and maintain normal reproductive function which is not necessary physiological activity for body. When body is in situation of low energy availability, namely deficient energy intake and (or) excessive energy expend, the energy redistribution will happen accompanied with reduced reproduction function. It can manifest as inhibition of hypothalamic-pituitary-ovary axis to different extents and ovulation dysfunction, menstrual disturbance and infertility as clinical symptoms. Long term energy deficiency can result in decrease of body fat, while the adipose tissue play key role in the relationship between nutrition and reproduction, thus exerting an influence on menarche initiation and menstrual cycle maintenance. The female athlete triad and anorexia nervosa are two typical examples of pathological situation under energy deficiency and low body fat over long term. Now, in order to restore body fat, we consider decreasing exercise consumption and increasing diet intake to increase body fat rate as necessary conditions for reproductive rehabilitation. In this review, we will focus on the influences of energy deficiency and low body fat on female reproductive health.
Key words:
Energy metabolism; Functional hypothalamic amenorrhea; Reproductive health; Female athlete triad syndrome; Anorexia nervosa
Contributor Information
Lu Ye
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Chen Chao
School of Athletic Performance, Shanghai University of Sport, Shanghai 200438, China
Zhou Yifan
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Zhao Yuting
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Wang Yulu
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Chen Hang
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Zhang Feifei
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
Li Xin
Department of Reproductive Endocrinology,the Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China