Review
Emerging molecular diagnostic technologies for point-of-care testing: applications and prospects
Huang Qunfang, Xun Zhen, Ou Qishui
Published 2023-10-19
Cite as Chin J Lab Med, 2023, 46(10): 1104-1108. DOI: 10.3760/cma.j.cn114452-20230830-00099
Abstract
Molecular diagnostic technologies are critical diagnostic tools in clinical research. Point-of-care testing (POCT) presents numerous advantages such as portability, rapidity, accuracy, and cost-effectiveness, facilitating timely identification of infection sources and control of infectious disease transmission. This article explores the emerging molecular diagnostic technologies that can be used for POCT, including digital loop-mediated isothermal amplification technology and the clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins system, while also discussing their future prospects.
Key words:
Gene amplification; Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins system; Point-of-care testing
Contributor Information
Huang Qunfang
Department of Laboratory Medicine, Fujian Key Laboratory of Laboratory Medicine, Gene Diagnosis Research Center, Fujian Clinical Research Center for Laboratory Medicine of Immunology, The First Affiliated Hospital, Fuzhou 350005, China
Xun Zhen
Department of Laboratory Medicine, Fujian Key Laboratory of Laboratory Medicine, Gene Diagnosis Research Center, Fujian Clinical Research Center for Laboratory Medicine of Immunology, The First Affiliated Hospital, Fuzhou 350005, China
Ou Qishui
Department of Laboratory Medicine, Fujian Key Laboratory of Laboratory Medicine, Gene Diagnosis Research Center, Fujian Clinical Research Center for Laboratory Medicine of Immunology, The First Affiliated Hospital, Fuzhou 350005, China