Review Article
Obesity and male reproductive health: An update
Qi Ruibing, Chen Bing, Li Zhengming
Published 2023-12-25
Cite as Chin J Endocrinol Metab, 2023, 39(12): 1083-1088. DOI: 10.3760/cma.j.cn311282-20230511-00219
Abstract
Obesity has become a growing epidemic that seriously affects the quality of human life. Obesity not only adds the burden to the body but may have negative impacts on various body systems and organs, such as the cardiovascular and metabolic systems. In recent years, some studies have shown that obesity also negatively affects the reproductive system and influences male reproductive health. Male reproductive health is not only related to the normalization of male reproductive function but also plays a role in the ability to conceive healthy offspring. This article summarizes research progress on the effects of obesity on male reproductive health, including endocrine hormone disruption, reproductive organ structural damage, increased oxidative stress, and reproductive cell epigenetic alterations, providing insights for a deeper understanding of the influence of obesity on male reproduction and potential treatments.
Key words:
Obesity; Oxidative stress; Epigenetics; Testosterone; Leptin; Inhibin B
Contributor Information
Qi Ruibing
Department of Endocrinology and Metabolism, Wuming Hospital of Guangxi Medical University, Nanning 530199, China
Chen Bing
Department of Endocrinology and Metabolism, Wuming Hospital of Guangxi Medical University, Nanning 530199, China
Li Zhengming
Department of Endocrinology and Metabolism, Guangxi Academy of Medical Sciences and People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China