The detection of lupus anticoagulant (LA) is an important part of laboratory diagnosis for antiphospholipid syndrome and systemic lupus erythematosus. As the test is based on coagulation time, results of LA are sensitive to various anticoagulants. There are widespread irregularities on testing reagent selection, processes, report, and result judgment of LA in domestic laboratories, in addition, there is also a lack of understanding among clinicians regarding patients′ preparation and report interpretation for LA testing. This consensus integrates the recommendations of international LA testing guidelines and the current applicational situations in China, and proposes guidance on LA testing and reporting focusing on the above issues, in order to normalize the domestic LA testing process and reporting, to promote the rational interpretation and application of LA reports by clinicians, consequently to ensure accurate management of related diseases and clinical conditions.

Antiphospholipid syndrome; Lupus anticoagulant; Systemic lupus erythematosus; Clinical laboratory techniques