Objective To improve the early diagnosis and treatment of Kartagener syndrome.Methods The clinical presentation, radiography, ulfrasound cardiogram,electrocardiogram changes of 3 patients were studied,and the relatated literature was reviewed. Results Kartagener syndrome is a rare autosomal recessive genetic disease, recognized by the three symptoms of chronic sinusitis, bronchiectasis,situs inversus. The most common initial symptoms are cough, sputum and sinusitis. Conclusion If the patients with situs irversus have the clinical presentations and radiography of brouchiefasis,it should be thought of Katagener syndrome.