Objective To preliminarily investigate the cutoff value of Stroke Aphasic Depression Questionnaire Hospital Version （SADQ-H） in the diagnosis of post-stroke depres- sion. Methods Using receiver operating characteristic （ROC） curves, the total scores of 17-item Hamilton Depression Rating Scale （HAMD-17） ffeater than 7 points and Beck Depression Inventory （BDI-13） ffeater than 4 points were taken as the cutoff values for the assessment of depression. SADQ-H for the assessment of the depression classification standard in patients with post-stroke aphasia was investigated preliminarily by HAMD-17 （8-17 were mild depres- sion; 18-24 were moderate depression, and 〉24 was severe depression）. Results When HAMD- 17 was used as a standard, ROC area under curve （AUC） was 0. 909 （95% confidence interval [CI] 0.814-1.005）. When 19.50 was used as a cutoff value, the sensitivity, specificity, positive predictive value, negative predictive value, and K coefficient of SADQ-H were 82. 6%,91.7%, 87. 0%, 83.3%, and 0. 77, respectively. When BDI-13 was used as a standard, ROC AUC was 0. 916 （95% CI O. 824-1. 008）. When choosing 18.50 as a cutoff value of diagnosis, the sensitivity, specificity, positive predictive value, negative predictive value, and K coefficient of SADQ-H were 80. 0%, 90. 0%, 84. 0%, 90. 0%, and 0. 68, respectively. The classification standards of SADQ-H for the assessment of depression in patients with post-stroke aphasia were 19, 22 and 26 points. Conclusions When the cutoff value of SADQ-H was 19 points, it had higher sensitivity, specificity, positive predictive value and negative predictive value for the assessment of depression; 19, 22 and 26 points could be used as the classification diagnostic standard of SADQ-H in the assessment of depression in patients with post-stroke aphasia.