Origiral article
Clinical observation on the effects of hyperbaric oxygen on the daily life capability of the patients with Parkinson's disease
Hao Qian, Zhiqiang Xian, Shoulian Ran, Tao Lin, Kun Yan
Published 2016-06-28
Cite as Chin J Naut Med & Hyperbar Med, 2016, 23(3): 194-196. DOI: 10.3760/cma.j.issn.1009-6906.2016.03.007
Abstract
ObjectiveTo investigate the effects of hyperbaric oxygen(HBO)on the daily life activity of the patients with Parkinson's disease(PD).
MethodsThe life quality of 60 PD patients who underwent HBO therapy was assessed both before therapy and after 4 courses of HBO therapy by using the Parkinson's Disease Questionnaire-39(PDQ-39). Unified Parkinson's Disease Rating Scale(UPDRS)and Hoehn-Yahr Scale were applied to evaluate the motor function. At the same time, the dosage and changes in the levels of dopaminergic drugs both before and after HBO therapy were recorded and the derived results were assessed with t-test.
ResultsThe total PDQ-39 scores were significantly elevated after 4 courses of HBO therapy, as compared with those before therapy(P<0.05). Of all the indicators, mobility, activities of daily living(ADL), emotional status and bodily discomfort were most significantly improved as compared with those before therapy(P<0.05). At of status, UPDRS III scores(31.6±10.2)and Hoehn & Yahr scale scores(2.8±0.3)were all decreased significantly, as compared with those(45.3±6.2, 3.2±0.5)before HBO therapy(P<0.05). The daily dosage of dopaminergic drugs was reduced by 18.9% after therapy(P<0.05).
ConclusionsHBO therapy could significantly improve the daily life activity of the patients with PD.
Key words:
Parkinson's disease; Hyperbaric oxygen; Life quality
Contributor Information
Hao Qian
Guangzhou Xinhai Hospital, Guangzhou 510300, China
Zhiqiang Xian
Shoulian Ran
Tao Lin
Kun Yan
