Clinical Research
The correlation study of left ventricular systolic function calculated by automated cardiac motion quantification
Yuan Song, Bowen Zhao, Bei Wang, Xiaohui Peng, Lilong Xu, Heqing Guo, Xiang Pan
Published 2017-01-25
Cite as Chin J Ultrasonogr, 2017, 26(1): 7-11. DOI: 10.3760/cma.j.issn.1004-4477.2017.01.002
Abstract
ObjectiveTo explore the correlation of left ventricular systolic function calculated by automated cardiac motion quantification (aCMQ) and three-dimensional quantitative analysis (3DQA).
MethodsAccording to LVEF by 3DQA, patients were divided into abnormal cardiac function group (LVEF<50%) and normal cardiac function group (LVEF≥50%). Dynamic images from two chamber view (AP2), four chamber view (AP4) and three chamber view(AP3) of left ventricular long axis were acquired from 32 patients with abnormal cardiac function and 119 normal subjects. AP2 longitudinal strain (AP2LS), AP4 longitudinal strain (AP4LS) and AP3 longitudinal strain (AP3LS) as well as the left ventricular global longitudinal strain (LVGLS) were measured by aCMQ. While left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV) and LVEF were derived through aCMQ automatically calculated region of interest (ROI) driven automation. The correlation of left ventricular systolic function indexes obtained by aCMQ and 3DQA were compared.
ResultsNo significant differences were found between the two groups in gender, body mass index(BMI) and age (P>0.05). LVEF in abnormal group by 3QDA and aCMQ were much lower than those in normal group (P<0.01). The absolute values of AP2LS, AP4LS, AP3LS and LVGLS in abnormal group were significantly lower than those in normal group (P<0.01). LVEF by aCMQ in abnormal group was positively correlated with LVEF by 3QDA methods (r=0.91, P<0.01); LVEF by aCMQ in normal group was positively correlated with LVEF by 3QDA (r=0.73, P<0.01). The left ventricular global longitudinal strain (LVGLS) measured by aCMQ was negatively correlated with LVEF by 3QDA(r=-0.815, P<0.01). LVEF measured by aCMQ and 3DQA showed high inter-observer and intra-observer agreements in Bland-Altman charts.
ConclusionsaCMQ has preferable repeatability. Comparing with the traditional measurement method, LVEF measured by aCMQ has higher correlation with that measured by 3QDA. aCMQ can be a new and relatively accurate method to evaluate the left ventricular systolic function.
Key words:
Echocardiography; Ventricular function, left; Speckle tracking imaging
Contributor Information
Yuan Song
Department of Diagnostic Ultrasound &
Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine &
Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, China
Bowen Zhao
Bei Wang
Xiaohui Peng
Lilong Xu
Heqing Guo
Xiang Pan
