Objective To analyze the clinical features of accommodation dysfunction and convergence dysfunction in asthenopia and to evaluate the effectiveness of vision therapy.Methods Seventy-five patients with visual fatigue were recruited in Optometric Center of Tianjin Eye Hospital from June 2012 to April 2013.All patients had routine eye examinations to exclude eye disease.Based on the results of binocular vision examination and cycloplegic refraction,personalized vision therapy was performed for every patient.On the basis of the refractive,every patient performs office-based vision therapy 1-2 times a week with home reinforcement.It conducted a total of 14 times.All data were rechecked and statistically analyzed by Paired-samples t Test.Results There were 58 cases of convergence insufficiency (77.3％),5 cases of convergence excess (6.7％),12 cases of accommodative dysfunction (16％).All patients' symptoms were relieved after 14 times vision therapy.The score of questionnaire of convergence insufficiency decreased from (22.6±7.4) to (11.6±4.7),the difference was significant (t =23.1,P =0.000).The near point of convergence (NPC) decreased from (13.1±1.9)cm to (5.4±1.2)cm,it showed a significant improvement (t =33.7,P-0.000).The positive fusional vergence at near increased from (17.3±6.5) △ to (29.7±4.9)△,the change was significant (t =-20.9,P =0.000).The amplitude of accommodation of accommodative dysfunction increased from (8.7±1.1)D to (14.9±1.4)D,the improvement was significant (t =-22.2,P =0.000).The monocular accommodative facility increased from (4.7±3.7)cpm to (15.1±2.2)cpm,the binocular accommodative facility increased from (3.4±3.4)cpm to (14.8±2.2)cpm,the differences were statistically significant (t =-12.96,P =0.000; t =-11.98,P=0.000).Conclusions The convergence insufficiency is the most common etiology of the asthenopia,the accommodative dysfunction is the second one.The function of accommodation and vergence improve obviously after reasonable vision therapy.The symptoms of visual fatigue relieve remarkably.