Clinical Research
Diagnosis and treatment of conjunctival papilloma
Jingjing QIAN, Shu LIANG, Yuyu WU, Jiamin TANG
Published 2018-06-10
Cite as Chin J Pract Ophthalmol, 2018, 36(6): 470-472. DOI: 10.3760/cma.j.issn.1006-4443.2018.06.016
Abstract
ObjectiveTo evaluate the clinical manifestations,the features of confocal microscopy images, the major treatments and their therapeutic effectiveness of conjunctival papilloma.
MethodsThis study applies retrospective analysis on 29 patients (29 eyes) who pathologically confirmed conjunctival papillomas from January 2013 to December 2016 in Affiliated Hospital of Nantong University, including 10 cases with conjunctival papilloma and the other 19 with limbal papilloma.Seven patients were examined by vivo confocal microscopy, and all patients were treated with "excision combined with freezing and amniotic membrane patching". The follow-up time was from 6 months to 4 years.
ResultsTwenty-five patients (25 eyes) had no recurrence after treatment. Two patients had postoperative recurrences and then no recurrence after retreatment was observed within 2 years of follow-up. Seven cases (grown cornea>4mm or infiltrated>1/2 ring of limbus) were examined by vivo confocal microscopy. The images showed atypical hyperplasia of corneal epithelial cells without any cell clusters similar to "cancer nests". Two patients lost follow-up after surgery.
ConclusionsExcision combined with freezing and amniotic membrane patching is an effective method for the treatment of conjunctival papilloma. There may be recurrence after treatment. Vivo confocal microscopy examination provides an important basis for preoperative diagnosis of conjunctival masses.
Key words:
Conjunctival papilloma; Confocal microscope; Surgery; Cryotherapy; Amniotic membrane patching
Contributor Information
Jingjing QIAN
Affiliated Hospital of Nantong University, Nantong 226001, China
Shu LIANG
Yuyu WU
Jiamin TANG