To systematically summarize the real experience of nursing students and clinical nurses after needle stick injury exposure, so as to provide the basis for the subsequent development of intervention strategies.

Databases including PubMed, The Cochrane Library, Web of science, Science direct and EBSCO host, PsychINFO, Scopus, CNKI, Wanfang, VIP and CBM were searched about the qualitative research on the real experience of needle stick injury exposure of nursing students and clinical nurses from the establishment of the database to September 2020. The qualitative research quality evaluation standard of Australia JBI evidence-based health care center was used for evaluation, and the result integration method was used for integration.

A total of 19 literatures were included, 16 literatures related to interns and junior nurses were included, and 79 research results were extracted. 11 literatures related to senior nurses were included, and 57 research results were extracted. The similar research results were summarized into six new categories, which were summarized into three integrated results, namely, the psychological experience of nurses with needle stick injuries; the impact of needle stick injuries on family life and personal value; and the need for support.

We should pay attention to the emotional and emotional experience of interns and clinical nurses after needle stick injury, provide professional psychological counseling, improve the occupational exposure monitoring and security system, and give full social support.

Students, nursing; Nurses; Needle stick injury; Occupational exposure; Psychological experience