Review
Progress of airway mucus plugs in bronchial asthma
Liu Tingting, Yin Ju, Guo Yan, Shen Kunling
Published 2022-09-26
Cite as Int J Pediatr, 2022, 49(9): 582-586. DOI: 10.3760/cma.j.issn.1673-4408.2022.09.002
Abstract
Mucus plugs is a feature of fatal asthma, which is the abnormally thick mucus accumulated in the airway of patients.The study of airway mucus plugs in asthmatic patients began 100 years ago.In addition to the manifestation of primary disease, asthma patients with mucus plugs may have acute exacerbation of asthma or poor treatment effect.At this time, we should pay attention to the existence of mucus plugs.Multidetector computed tomography can be used to identify and evaluate mucus plugs.This article briefly describes the generation of airway mucus, and introduces the formation mechanism, clinical characteristics, identification and scoring system of mucus plugs in asthmatic patients, and reviews the differential diagnosis and treatment of mucus plugs.
Key words:
Children; Asthma; Mucin; Mucus plugs
Contributor Information
Liu Tingting
China National Clinical Research Center of Respiratory Diseases, Respiratory Department of Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
Yin Ju
China National Clinical Research Center of Respiratory Diseases, Respiratory Department of Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
Guo Yan
China National Clinical Research Center of Respiratory Diseases, Respiratory Department of Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
Shen Kunling
China National Clinical Research Center of Respiratory Diseases, Respiratory Department of Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
Department of Respiratory, Shenzhen Children′s Hospital, Shenzhen 518038, China
