Review
Research progress of targeted therapy for thyroid carcinoma
Wang Yushu, Liu Jiayi, Wang Chao
Published 2022-07-05
Cite as Int J Immunol, 2022, 45(4): 437-440. DOI: 10.3760/cma.j.issn.1673-4394.2022.04.018
Abstract
Thyroid carcinoma is a common head and neck carcinoma in China, which seriously affects people's quality of life. The treatment of thyroid carcinoma includes surgery, iodine radiation therapy, chemotherapy and thyroid hormone suppression therapy, but the effect is not ideal for some poorly differentiated refractory tumors. With the continuous understanding of tumor molecular regulatory mechanism and carcinoma genetics, we have made new progress in understanding the molecular pathogenesis of different thyroid subtypes, which provides the possibility for immunotherapy and molecular targeted therapy. The molecular pathogenesis of thyroid carcinoma and its corresponding targeted drugs are reviewed.
Key words:
Thyroid carcinoma; Molecularly targeted therapies; Tyrosine kinase inhibitor
Contributor Information
Wang Yushu
Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China
Liu Jiayi
Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China
Wang Chao
Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China