Review
Research progress on the role of macrophages in echinococcosis and the regulation of macrophages by parasite-derived molecules
Yang Ning, Lin Renyong
Published 2023-03-20
Cite as Chin J Endemiol, 2023, 42(3): 246-251. DOI: 10.3760/cma.j.cn231583-20211122-00383
Abstract
As a major member of innate immunity, macrophage can eliminate pathogens through cell phagocytosis, antigen presentation and immune regulation, and play an important role in parasitic infections such as Echinococcus. Echinococcus can regulate the function of host macrophages through a variety of parasite-derived molecules, such as protein and nucleic acid molecules, and realize long-term parasitism in the host. This article focuses on the research progress of the role of macrophages in echinococcosis and the regulation of macrophages by parasite-derived molecules.
Key words:
Echinococcosis; Macrophages; Immunoregulation
Contributor Information
Yang Ning
State Key Laboratory for the Causes and Prevention of High Incidence Diseases in Central Asia, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China
Lin Renyong
State Key Laboratory for the Causes and Prevention of High Incidence Diseases in Central Asia, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China