Original Article
Preliminary clinical study of gastric-peroral endoscopic pyloromyotomy for pediatric patients with congenital hypertrophic pyloric stenosis (with video)
Zhang Hanhua, Fang Ying, Ren Xiaoxia, Yang Hongbin, Han Yanan, Ge Kuku, Wang Feng, Zhou Pinghong
Published 2020-11-20
Cite as Chin J Dig Endosc, 2020, 37(11): 805-809. DOI: 10.3760/cma.j.cn321463-20200228-00139
Abstract
ObjectiveTo evaluate the efficacy and safety of gastric-peroral endoscopic pyloromyotomy (G-POEM) for congenital hypertrophic pyloric stenosis (CHPS).
MethodsClinical data of 6 CHPS children who received G-POEM treatment in Xi′an Children′s Hospital from January 2019 to September 2019 were collected. Their operative data, perioperative management and procedure-related complications were summarized.
ResultsThe 6 children had mean daily age of 54.5 d (27-130 d). All of them successfully completed G-POEM, with mean operation time of 49.5 min (34-150 min). No postoperative fever, gastrointestinal bleeding or abdominal abscess occurred. The mean hospitalization time was 12.5 d (10-22 d). The mean follow-up time was 4.2 months (3.3-8.6 months). After one-month postoperative follow-up, the pylorus showed obvious dilation to 1.1 cm (0.9-1.5 cm) compared with that before treatment of 0.3 cm ( 0.1-0.5 cm). After one-month and three-month postoperative follow-up, the mean body weight of the children increased by 0.9 kg (0.4-1.6 kg) and 3.2 kg (2.6-3.5 kg), respectively. After three months of postoperative follow-up, all children reached the standard body weight.
ConclusionG-POEM for infant CHPS is safe and effective, which could be a new option.
Key words:
Pyloric stenosis, hypertrophic; Congenital abnormalities; Gastric peroral endoscopic pyloromyotomy
Contributor Information
Zhang Hanhua
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Fang Ying
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Ren Xiaoxia
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Yang Hongbin
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Han Yanan
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Ge Kuku
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Wang Feng
Department of Gastroenterology, Xi′an Children′s Hospital, Xi′an 710003, China
Zhou Pinghong
Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China
