By binding to their receptors, retinoids can regulate the proliferation and differentiation of epithelial cells, exert anti-inflammatory and immunomodulatory effects, and are used to treat various kinds of autoimmune inflammatory diseases. They participate in immune defense and anti-inflammatory process by influencing various kinds of cytokines and immunocytes such as neutrophils, monocytes/macrophages, dendritic cells, mast cells, T cells and B cells. In addition, retinoids have been applied in the treatment of many inflammatory skin diseases such as psoriasis, acne, lichen planus, and so on, and have shown favorable therapeutic effects.

Retinoids; Immunomodulation; Inflammation; Skin diseases; Therapeutic uses