Etiology and clinical types of viral hepatitis in Wenling city
WANG Xiu-zhen, MAO Wen-zhong, ZHANG Chang, LIU Xue-feng, YAN Ming-he, CAI Li-min,, LING Qiao, HUANG Xi-tian, MA Chun-lian, XIE Hong-sheng
Published 2011-08-25
Cite as Inter J Epidemiol Infect Dis, 2011,38(04): 245-247. DOI: 10.3760/cma.j.issn.1673-4149.2011.04.009
Abstract
Objective To investigate the etiology and clinical types of sporadic virus hepatitis in wenling city and to provide the base for the preventive strategy. Methods The data of 3317 sporadic viral hepatitis cases in the Affiliated Wenling Hospital of Wenzhou Medical College were analysed retrorespectively. Results Of the 3317 cases, the rates of hepatitis A, B,C,D, E,G, coinfection and infection of uncertain type were 1.63% ,64.97% ,0.66% ,0.12% ,9.52%,0.06%,16.79% and 6.24% respectively.The clinical types included 1181 eases of chronic hepatitis (35.60%),965cases of hepatocirrhosis(29.09% ) ,904 cases of acute hepatitis(27.25% ), 175 cases d liver cancer(5.28% ) ,56 cases of serious hepatitis( 1.69% ),36 cases of cholestatic hepatitis( 1.09% ). The rates of hepatitis B in chronic hepatitis,hepatocirrhosis, serious hepatitis, liver cancer and coinfection were 74.68% ,82.80% ,71.43% ,97.71% and 88.51%respectively. The incidence of hepatitis A reduced, while the incidence of hepatitis B and E increased in acute hepatitis. The rate of uncertain type hepatitis was 18.03% in acute hepatitis. Conclusions Most patients are infected with hepatitis B virus in Wenling city, especially in adults. Extended vaccination and strengthening the management of volunteer donors and blood transfusion are effective measures to prevent the transmission. Meanwhile, the hepatitis E epidemic should be controlled strictly, and the study of new hepatitis virus should be strengthened.
Key words:
Hepatitis, viral,human; Etiology; Clinical types
Contributor Information
WANG Xiu-zhen
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
MAO Wen-zhong
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
ZHANG Chang
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
LIU Xue-feng
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
YAN Ming-he
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
CAI Li-min,
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
LING Qiao
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
HUANG Xi-tian
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
MA Chun-lian
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China
XIE Hong-sheng
Department of Infectious Diseases, the Affiliated Wenling Hospital of Wenzhou Medical College, Wenling 317500, China