To understand the epidemiological and clinical characteristics of brucellosis, and to further strengthen the understanding of brucellosis in clinical doctors.

The clinical data of 474 brucellosis patients in Heilongjiang Provincial General Administration of Reclamation and Reclamation in 2017 were retrospectively analyzed and summarized.

Brucellosis could occur in all seasons of the year, with the peak incidence from April to June (198 cases, 41.77%) . The male to female ratio was about 4∶1, and the age of onset was mainly 19-50 years old (325 cases, 68.57%) . The main source of infection was sheep and cattle (420 cases, 88.61%) . The main clinical manifestations were fever (421 cases, 88.82%) , hyperhidrosis (378 cases, 79.75%) , fatigue (398 cases, 83.97%) and arthralgia (364 cases, 76.79%) . There were 396 cases misdiagnosed as upper respiratory tract infection, and some patients who had arthralgia were commonly misdiagnosed as arthritis and spinal tuberculosis. After several months’ follow-up, except for 14 cases of occasional joint pain, the rest cases were stable and had no recurrence.

Most brucellosis patients have clear contact history, and the clinical manifestation is atypical. Therefore, more attention should be paid to the contact history and supplementary way should be used for reducing misdiagnosis.

Brucellosis; Epidemiology; Clinical characteristics