Original Article
Safety and efficacy of Ningmitai capsule combined with western medicine in the treatment of chronic prostatitis
Zhongjin Fang, Zaoqing Chen, Zhaocun Yu, Changjun Yang, Huasheng Huang
Published 2016-12-15
Cite as Chin J Prim Med Pharm, 2016, 23(24): 3769-3772. DOI: 10.3760/cma.j.issn.1008-6706.2016.24.022
Abstract
ObjectiveTo observe the efficacy and safety of levofloxacin hydrochloride combined with Tensaw complex symplectic and Ningmitai in the treatment of chronic prostatitis.
Methods126 patients with chronic prostatitis were selected.The patients were randomly divided into two groups with 63 cases in each group.The control group was given levofloxacin tablets + tamsulosin hydrochloride.The observation group was given levofloxacin tablets + tamsulosin hydrochloride + Ningmitai capsule.The treatment course was 2 weeks.The therapeutic effect was evaluated after two courses of treatment.Chronic prostatitis symptom index(NIH-EPSI) score before and after treatment, and white blood cell of prostate were compared, and the therapeutic effect and safety of two treatments were compared before and after treatment.
ResultsThe white blood cell count in the observation group after treatment was lower than that of the control group, and the difference was statistically significant(t=7.612, P<0.01). After treatment, in the observation group, the NIH-CPSI scale of pain or discomfort symptoms[(5.32±1.67)points], quality of life[(3.60±1.34)points]and voiding symptoms[(3.28±0.93)points], total score[(13.95±4.77)points] were lower than those of the control group[(9.21±1.88)points, (4.69±1.43)points, (4.65±1.20)points, (20.39±5.24)points], the differences were statistically significant(t=16.786, 6.987, 6.641, 13.876, all P<0.01). The total effective rate of the observation group was 87.3%, which was higher than 66.7% of the control group, the difference was statistically significant(χ2=7.987, P<0.05). In the two groups, there were no adverse reactions during orthostatic hypotension, drug eruption etc.
ConclusionLevofloxacin hydrochloride combined with Tensaw complex symplectic and Ningmitai has satisfactory effect in the treatment of chronic prostatitis, with good security.
Key words:
Prostatitis; Levofloxacin; Tamsulosin; Ningmitai
Contributor Information
Zhongjin Fang
Department of Urology, Houjie Hospital Affiliated to Guangdong Medical University, Dongguan, Guangdong 523945, China
Zaoqing Chen
Zhaocun Yu
Changjun Yang
Huasheng Huang