Review
Mechanism of venous thrombosis in patients with multiple myeloma
Zou Yaqian, Cai Huili, Zhou Mi, Chen Li, Chen Haidan, Guo Jingming
Published 2021-05-20
Cite as J Chin Physician, 2021, 23(5): 786-789. DOI: 10.3760/cma.j.cn431274-20200615-00805
Abstract
Multiple myeloma is a plasma cell disease with the second highest incidence among hematological malignancies. Its risk of concurrent thrombosis is high, which greatly affects the quality of life and even endangers life of multiple myeloma patients. The pathogenesis of thrombosis in patients with multiple myeloma is complex, which is still unclear. However many mechanisms are considered to be related to hypercoagulable state in patients with multiple myeloma. Currently, there is a lack of thrombosis risk assessment model for multiple myeloma. Therefore, this paper reviews the research and the latest progress of venous thrombosis in patients with multiple myeloma, and provides a theoretical basis for the prevention and treatment of thrombosis.
Key words:
Multiple myeloma; Venous thrombosis; Blood coagulation disorders
Contributor Information
Zou Yaqian
Department of Hematology, Yichang Central People′s Hospital, the First Clinical Medical College of Three Gorges University, Yichang 443000, China
Cai Huili
Department of Hematology, Yichang Central People′s Hospital, the First Clinical Medical College of Three Gorges University, Yichang 443000, China
Zhou Mi
Department of Hematology, Yichang Central People′s Hospital, the First Clinical Medical College of Three Gorges University, Yichang 443000, China
Chen Li
Department of Hematology, Yichang Central People′s Hospital, the First Clinical Medical College of Three Gorges University, Yichang 443000, China
Chen Haidan
Department of Hematology, Yichang Central People′s Hospital, the First Clinical Medical College of Three Gorges University, Yichang 443000, China
Guo Jingming
Department of Hematology, Yichang Central People′s Hospital, the First Clinical Medical College of Three Gorges University, Yichang 443000, China
