Original Article
Epidemiological investigation of chronic lymphocytic leukemia in Hunan Province: based on the calculation of the registration and reporting system of malignant tumors in Hunan Province
Tang Yiqian, Li Heng, Liao Xianzhen, Yan Junxia, Yan Shipeng, Xu Kekui, Peng Hongling
Published 2022-03-20
Cite as J Chin Physician, 2022, 24(3): 355-360,365. DOI: 10.3760/cma.j.cn431274-20210618-00669
Abstract
ObjectiveTo understand the distribution and epidemiological characteristics of chronic lymphocytic leukemia (CLL) in Hunan Province.
MethodsAccording to the audit methods and evaluation criteria specified by the National Cancer Registration Center, the registration data of CLL reported by 24 tumor registries was included. Through the research method of retrospective analysis, the selected registry data was calculated and analyzed according to the year, administrative division, urban and rural areas, gender and age.
ResultsA total of 104 newly diagnosed CLL patients were diagnosed in Hunan Province from 2014 to 2015, with an average annual morbidity of 0.39/100, 000. The morbidity in 2014 and 2015 was 0.39/100, 000 and 0.39/100, 000, respectively. The annual average morbidity in Zhuzhou was 0.8/100, 000, which was the highest among municipalities. The annual average morbidity in Kaifu District of Changsha was 1.65/100, 000, which was the highest among district-level administrative divisions. The morbidity of urban was higher than that of rural (Urban vs Rural, P=0.006). The male to female morbidity was 1.7∶1. The cases were mainly concentrated in the 61-70-year-old population, accounting for 33.65% of all cases (35/104). There were 64 patients died of CLL in Hunan Province from 2014 to 2015, and the average annual mortality was 0.24/100, 000. The mortality in 2014 and 2015 was 0.22/100, 000 and 0.26/100, 000, respectively. The average annual mortality in Hengyang was 0.53/100, 000, which was the highest among municipalities. The average annual mortality in Furong District of Changsha was 0.74/100, 000, which was the highest among district-level administrative divisions. The mortality of urban was higher than that of rural but with no significant difference (P=0.006). The male to female mortality rate was 1.4∶1. The deaths were mainly concentrated in the 71-80-year-old population, accounting for 29.69% of all deaths (19/64).
ConclusionsThe morbidity of CLL in Hunan Province is much lower than that of European and American populations, and it mainly occurs in the elderly people. It is more common in men. The morbidity of urban is higher than that of rural and morbidity in Zhuzhou is the highest. The death of CLL patients was mainly in middle-aged and elderly population, with more males. The mortality of urban is slightly higher than that of rural and the mortality in Hengyang is the highest.
Key words:
Epidemiologic studies; Leukemia, granulocytes, chronic; Incidence; Mortality
Contributor Information
Tang Yiqian
Department of Hematology, the Second Xiangya Hospital of Central South University, Changsha 410011, China
Li Heng
Department of Hematology, the Second Xiangya Hospital of Central South University, Changsha 410011, China
Liao Xianzhen
Hunan Provincial Cancer Prevention and Treatment Office, Changsha 410013, China
Yan Junxia
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China
Yan Shipeng
Hunan Provincial Cancer Prevention and Treatment Office, Changsha 410013, China
Xu Kekui
Hunan Provincial Cancer Prevention and Treatment Office, Changsha 410013, China
Peng Hongling
Department of Hematology, the Second Xiangya Hospital of Central South University, Changsha 410011, China
