Objectives To explore the clinical effect of the treatment of upper ureteric calculi by ureteroscopic holmium laser lithotripsy combined with ureteral block calculus extraction catheter.Methods Retrospectively analyzed the clinical data of the patients of upper ureteric calculi (23 cases) treated by ureteroscopic holmium laser lithotripsy combined with ureteral block calculus extraction catheter in the first half of this year.There were 6 cases with the calculi at the level of L2,9 at the level of L3,8 at the level of L4.The size varied from (0.7cm * 1.1 cm) to (1.4cm * 1.8cm),with the average of 1.0cm * 1.4cm.Results 22 out of the 23 cases were successfully implanted with uteroscope and block calculus extraction catheter at the first attempt,with the 95.7％ successful rate of lithotripsy at first attempt.The operation time was from 15 to 45 minutes,with the average of 25 ± 10 minutes.Postoperative hospital stay was from 1 to 4 days,with the average of 2.5 ± 1.0 days.1 case of the calculi moved up into the kidney and was successfully expelled by indwelling D-J tube in operation and employing extracorporeal shock wave lithotripsy (ESWL) after operation.All the cases were with little hemorrhage,no complications of perforation,mucosal antrectomy,etc.No patient had fever or bacteremia after operation.No remained calculi found in reexamination by abdominal plain films and ultrasonography in urology 3 to 4 weeks after operation.Conclusions It is a safe and effective method to treat the upper ureteric calculi by ureteroscopic holmium laser lithotripsy combined with ureteral block calculus extraction catheter.Ureteral block calculus extraction catheter is a safe and effective tool,which can significantly reduce the calculus shift in ureterscopic lithotripsy,enhance the successful rate of lithotripsy at first attempt,and shorten the time of operation and hospital stay,thus to reduce the hospitalization expenses.It could also avoid the expensive price of flexible ureteroscope as well as the risks and complications by percutaneous nephroscope lithotripsy.